There have, however, been signs of a developing resistance to azithromycin , mostly related to resistant strains of syphilis that first emerged in the s with the introduction of antibiotics. So, while epidemiologists continue to monitor for signs of antibiotic resistance, penicillin should be considered the safest and most reliable means of treating syphilis.
According to the CDC, anyone exposed through sexual contact with a person who has primary, secondary, or early latent syphilis should be treated according to the following recommendations:. The following sex partners of people who have syphilis are considered at risk for infection and should be confidentially notified of the exposure and need for evaluation:. An intramuscular injection of penicillin G is the preferred treatment for all stages of syphilis. Generally, a single shot of long-acting Benzathine penicillin G will cure a person of primary, secondary, or early latent syphilis.
Late latent and tertiary syphilis are treated with three doses given at one-week intervals. Even with there is an allergy, Penicillin G is still the treatment of choice.
Your healthcare provider may do allergy testing or other tests to verify if there is a true high-risk allergy to penicillin. Most patients are able to safely get the standard treatment of Penicillin. In rare cases, there are other options to treat with oral and IV antibiotics, which can be tailored to the stage of syphilis. Penicillin G is the only recommended treatment. Pregnant persons who are allergic to penicillin would need to undergo penicillin desensitization in a hospital.
This typically involves 14 oral doses of penicillin given in incrementally increasing doses over four to 12 hours to reduce the risk of a hypersensitive reaction to intramuscular penicillin G. Yes, always. If you have had sex with someone within 90 days of their syphilis diagnosis, you would be presumptively treated even if your own syphilis test is negative.
You would need to abstain from sex until the syphilis sores chancres are completely healed. Persons with vaginas or those who were exposed through anal sex may need a medical examination, as the sores may be internal and not readily seen. Follow-up testing is used to ensure that the treatment worked. Syphilis antibody levels will be elevated after treatment, and they will gradually subside over time.
A four-fold decrease in antibodies after one year is considered a treatment success. Most people are advised to undergo retesting six to 12 months after the completion of treatment. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Centers for Disease Control and Prevention. Last reviewed April 13, Centers of Disease Control and Prevention. Updated July 22, Syphilis During Pregnancy.
Stamm LV. Syphilis: antibiotic treatment and resistance. Epidemiol Infect. Sexually transmitted infections treatment guidelines July 22, Tipple C, Taylor GP. Low enough levels confirm adequate treatment. If a person receives a diagnosis of syphilis, they must notify any sexual partners.
Their partners should also undergo testing. Local services are available to notify sexual partners of their potential exposure to syphilis, enable testing and, if necessary, administer treatment. Healthcare professionals will also recommend testing for HIV.
Many providers now offer at-home tests for syphilis. Many people with an STI will not be aware of it. Therefore, it is a good idea to talk to a doctor or request a test in the following situations:. Syphilis develops when T. The infection can pass from a woman to a fetus during pregnancy or to an infant during delivery. This type is called congenital syphilis. Syphilis cannot spread through shared contact with objects, such as doorknobs, eating utensils, and toilet seats.
Having syphilis once does not mean that a person has protection from it going forward. The VDRL test can test for the presence of syphilis. Learn more about how what it is, how it works, and symptoms a person should look for. The secondary stage of syphilis has symptoms including sores on the genitals, mouth, and anus. Diagnosis involves a physical exam. Learn more about…. The rapid plasma reagin test is a simple blood test that screens for syphilis. Doctors recommend the RPR test when they suspect that a person may have….
What to know about syphilis. Medically reviewed by Jill Seladi-Schulman, Ph. What is syphilis? Symptoms Is it curable? Treatment When is it safe to have sex? Tests and diagnosis Causes Risk factors Prevention Syphilis is a sexually transmitted bacterial infection. Is it curable? When is it safe to have sex? Tests and diagnosis. Risk factors. Latest news Adolescent depression: Could school screening help?
Exposure to air pollutants may amplify risk for depression in healthy individuals. Related Coverage. However, treatment will not undo any damage that the infection has already caused. What is the treatment for syphilis? March Syphilis Pocket Guide for Providers pdf icon — A booklet for providers containing need-to-know details on the diagnosis, treatment, and prevention of syphilis.
November 30, Syphilis Self-Study Module external icon — An online learning experience that helps users learn how to manage syphilis. November 1, Related Content. STDs Home Page. Find an STD testing site near you. ZIP Code:.
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