What is gnrh agonist

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Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Related Articles. When Does Menopause Start? What Is Anovolation? The other common side effects are: insomnia decreased libido headaches mood swings vaginal dryness decreased breast size increased breast size acne muscle pains dizziness depression.

The menopausal-type symptoms usually disappear soon after treatment ceases. Effectiveness for pain symptoms All the GnRH agonists work in the same way, so they are equally effective in regressing endometrial implants and reducing pelvic pain symptoms [1]. Effectiveness for infertility The GnRH agonists — like all the hormonal treatments for endometriosis — do not improve your chances of conceiving, without any reproductive techniques, so they should not be used as a treatment for infertility.

Keeping track You should see your gynaecologist about 6—8 weeks after beginning your course of a GnRH agonist to discuss how the treatment is progressing. Pregnancy and breastfeeding GnRH agonists should not be used during pregnancy. Interactions GnRH agonists may interact with other medicines. Recommendations on the use of GnRH in the management of endometriosis. In: Lunenfeld B ed. Efficacy of every-other-day administration of conugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis.

Gynaecol Obstet Invest ; Prospective randomised double-blind trial of 3 versus 6 months of nafarelin therapy for endometriosis associated pelvic pain. Fertil Steril ; Hum Reprod ;16 11 Prentice A. Progestagens and anti-progestagens for pain associated with endometriosis. In: The Cochrane Library, Issue 3. The impact of preoperative gonadotropin-releasing hormone agonist treatment on laparoscopic excision of ovarian endometriotic cysts.

Hemmings R. Combined treatment of endometriosis. GnRH agonists and laparoscopic surgery. J Reprod Med ;43 3 Postoperative administration of monophasic combined oral contraceptives after laparoscopic treatment of ovarian endometriomas: a prospective, randomised trial.

Am J Obstet Gynecol ; Effects of pre-treatment with GnRH-Agonists on bone mineral density in patients with endometriosis. Long-term pituitary down-regulation before in vitro fertilization IVF for women with endometriosis. Cochrane Database of Systematic Reviews ; Issue 1. Stay up to date Register for endometriosis news: Email Address. Connect to the endometriosis community on Facebook. This article summarizes the application of GnRH agonist drugs in clinical practice, their side effects, and important information for patient use.

Abstract Gonadotropin-releasing hormone agonists are a relatively new class of drugs, which, when chronically administered, result in marked reductions in blood levels of testosterone and estrogen.

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