What is the difference between scar tissue and normal skin tissue

Histochem Cell Biol, , 1 : 1— Ghahary A, Ghaffari A. Role of keratinocyte-fibroblast cross-talk in development of hypertrophic scar. Article PubMed Google Scholar. Keratinocyte-fibroblast interactions in wound healing.

J Invest Dermatol, , 5 — Reinke JM, Sorg H. Wound repair and regeneration. Eur Surg Res, ,49 1 — Non-thermal plasma suppresses bacterial colonization on skin wound and promotes wound healing in mice. Oriented cell division: new roles in guiding skin wound repair and regeneration. Biosci Rep, ,35 6. Biomechanics of scar tissue and uninjured skin.

Adv Wound Care, ,2 2 — Jones N. Scar tissue. Low-intensity treadmill exercise promotes rat dorsal wound healing. Epidermal stem cells and skin tissue engineering in hair follicle regeneration.

World J Stem Cells, ,7 4 — When I was 10 or 11 years old, I hurt my knee at summer camp when I fell running around a gravel-covered walkway with some of my bunkmates. I fell hard enough that a few tiny pieces of gravel actually embedded themselves under the skin that covered my kneecap.

In the infirmary, after the nurses wiped away the blood and washed the gravel bits out of the skin, they placed a bucket under my leg and poured rubbing alcohol over it. It hurt, but at least I didn't get an infection. What I did get, however, was a nice scar. Then there was the time I stabbed my hand with a knife while attempting to open boxes in my college dorm room.

Despite my best efforts, that, too, resulted in a scar on my left hand, in the space between my thumb and first finger. Nearly everyone has a good scar story or two, or three they can tell in an effort to one-up their friends' stories. But what exactly is scar tissue anyway? Scabs protect the wound from infection - and then form scars Credit: iStock. For one thing, a scar is a virtual certainty following a wound of any sort, at least to some degree.

That's because a scar is the natural outcome of the body's normal healing process as it works to repair the skin or another of its organs.

This article is part of Nature Outlook: Skin , an editorially independent supplement produced with the financial support of third parties. About this content. Nishiguchi, M. Cell Rep. PubMed Article Google Scholar. Rinkevich, Y. Science , aaa Ito, M. Nature , — Plikus, M. Science , — Seifert, A. Simkin, J. Holmes, J. IV et al. Burn Care Res. Centanni, J. Download references. Article 03 NOV Outlook 27 OCT News Explainer 10 NOV News 04 NOV News Feature 03 NOV Article 27 OCT Research Highlight 22 OCT Article 06 OCT Yale Cancer Center.

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Credit: Marco Melgrati. You have full access to this article via your institution. Download PDF. References 1. PubMed Article Google Scholar 2. PubMed Article Google Scholar 3. PubMed Article Google Scholar 4. PubMed Article Google Scholar 5. Skin wound healing is a complex event, and interrupted wound healing process could lead to scar formation.

The aim of this study was to examine the morphological changes of scar tissue.